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Structural Investigation of mTORC1 Regulation at the Lysosomal Membrane
The mechanistic target of rapamycin complex 1 (mTORC1) regulates cell growth andcatabolism by phosphorylating key substrates in response to nutrient fluctuations. Recruitment of mTORC1 to the lysosomal membrane by the Rag-Ragulator complex is important for activation of its kinase activity and inter
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