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A Low Containment CCHFV Entry Screening Platform Identifies Compounds with Antiviral Activity against Authentic CCHFV

Spinoza, N. et al.
bioRxiv / medRxiv · Papers · License: CC0 1.0
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microbiology
Backgrounds Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne nairovirus that can cause severe human disease in the endemic areas, and no licensed antiviral is broadly available. Antiviral discovery is constrained by the requirement to study authentic CCHFV under biosafety level 4 (BSL-4
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