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Influence of Ozone Therapy on Postoperative Pain Relief in the Surgical Treatment of Lower Third Molars: Randomized Controlled Trial

Azienda Ospedaliera Ordine Mauriziano di Torino · 2022
ClinicalTrials.gov · Datasets · License: Public Domain · 2022
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Patients will undergo a split-mouth protocol which includes: a control group: in which the extraction of the lower third molar will be performed according to the standard protocols of the structure. A study group: in which ozone will be used in addition, in two formulations: gaseous, injected into the site of the pre- and post-surgery operation, and topical, in the form of a gel, applied at the end of the operation and for home use according to therapeutic scheme prescribed at the time of discharge. Primary objective: To evaluate whether the use of ozone in patients undergoing extraction of impacted third molars reduces post-operative pain 7 days after surgery. Secondary objectives: * Evaluate the functional limitation in opening the mouth (trismus) 7 days after surgery. * Evaluate if there is a reduced intake of analgesic drugs in the 7 days following the operation. * Evaluate the perceived quality of life in the 7 days following the intervention.
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