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Material Balance Study of TQ-B3525

Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · 2023
ClinicalTrials.gov · Datasets · License: Public Domain · 2023
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chronic-kidney-diseasesmagnetic-resonance-imaging
A clinical study to investigate the absorption, metabolism and excretion of \[14C\] TQ-B3525 in Chinese adult male healthy subjects, aiming to quantitatively analyze the total radioactivity in the excreta of male healthy subjects after oral administration of \[14C\] TQ-B3525, obtain the data of human radioactive excretion rate and main drainage routes, investigate the distribution in whole blood and plasma, the distribution in plasma and the pharmacokinetics of total radioactivity in plasma, and identify the main metabolites, To determine the main biotransformation pathway and obtain the pharmacokinetic parameters of TQ-B3525 and its metabolites in plasma.
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