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Evaluation of the Value of 18F-Fluoromisonidazole (18F-FMISO) Positron Emission Tomography Hypoxia Imaging in Idiopathic Pulmonary Fibrosis

Centre Hospitalier Universitaire Dijon · 2023
ClinicalTrials.gov · Datasets · License: Public Domain · 2023
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idiopathic-pulmonary-fibrosis
Idiopathic pulmonary fibrosis (IPF) is a rare, chronic, lethal disease of unknown etiology and with a variable course. There is currently no test in routine care that can assess both the anatomical and functional damage of the disease at an early stage. This is the first human study in IPF to evaluate the value of a non-invasive tracer, 18F-fluoromisonidazole (18F-FMISO), targeting hypoxia in IPF patients. This is a Phase I, proof-of-concept, single-center, open-label, parallel group study. It will include 2 groups: * 1 group of 10 IPF patients * 1 group of 10 healthy volunteers matched to IPF patients for age and gender
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