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Impact of Adjusted Creatinine Clearance on Carboplatin Dosing in Endometrial Cancer: A Retrospective Study

Katayama, Kentaro et al.
OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY · Papers
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endometrial-cancerneutropenia
Carboplatin (CBDCA) dosing is commonly determined using the Calvert formula, with creatinine clearance (Ccr) estimated by the Cockcroft–Gault formula. In Japan, where serum creatinine (sCr) is usually measured enzymatically, unadjusted Ccr may overestimate glomerular filtration rate and lead to CBDC
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