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Oral L-carnitine and Inflammatory and Nutritional Biomarkers in Maintenance Hemodialysis

Darya Chamani · 2020
ClinicalTrials.gov · Datasets · License: Public Domain · 2020
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hemodialysisinflammationlipid-profilemalnutrition
The goal of this clinical trial is to evaluate whether oral L-carnitine supplementation helps reduce inflammation and improve nutritional status in patients with end-stage kidney disease who are undergoing long-term hemodialysis. A total of 50 participants will be randomly assigned to receive either: * Oral L-carnitine solution (1 g, three times per week after dialysis), or * A placebo solution that looks and tastes the same but does not contain L-carnitine. The study will last for three months. Researchers will assess changes in: * Inflammatory markers (high-sensitivity C-reactive protein, hs-CRP) * Nutritional markers (serum albumin, ferritin) * Blood lipid profile (cholesterol, LDL, HDL, triglycerides) The findings from this study are expected to provide insights into the potential clinical benefits of oral L-carnitine supplementation in maintenance hemodialysis patients.
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