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Investigating STAT3 as a Driver of Pathology in Periodontitis

University of Chile · 2019
ClinicalTrials.gov · Datasets · License: Public Domain · 2019
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periodontitis
Periodontitis is a prevalent inflammatory condition that destroys tooth-supporting structures. This condition is associated with pro-inflammatory mediators that utilize STAT3 as an activator of specific genes related to inflammation and tissue destruction. STAT3 has not been studied in the context of periodontitis in humans. We propose that STAT3 is associated with periodontitis. This knowledge might help to further our understanding of periodontitis pathology
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