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Rapid Aryne-Enabled Aryl Functionalization via Mechanically Assisted Microscale Mixing
biophysicscomputational-biologyecologyevolutionary-biologygeneticsinfectious-diseasesphysiologyspace-science
Herein, we demonstrate that arynes can be generated and trapped efficiently through mechanically assisted microscale mixing on a standard vortex mixer. Brief vortex agitation enables ultra-fast generation and interception of these highly reactive intermediates with N-, O-, S-, and C-nucleophiles wit
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