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The Pharmacogenomics of Cisplatin-Induced Ototoxicity
biochemistry-and-cell-biologybiological-sciencescisplatinevolutionary-biologygeneticspharmacogenomics
Cisplatin is a first line treatment for a wide range of cancers; one commonly observed adverse drug reaction (ADR) of cisplatin is ototoxicity. Onset of ototoxicity from cisplatin is inconsistent and no single risk factor can reliably predict whether a patient will develop ototoxicity. A genetic fac
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