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Dissociation between heart rate reduction and left ventricular filling pressure in heart failure with preserved ejection fraction: a meta-analysis of ivabradine trials
Въведение: Към намаляването на сърдечната честота (СЧ) обикновено се пристъпва за подобряване на диастолното пълнене и намаляване на налягането на пълнене на лявата камера (ЛК) при сърдечна недостатъчност със запазена фракция на изтласкване (СНзФИ). Ивабрадин селективно понижава СЧ без директни миок
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