bioRxiv / medRxiv
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CC BY-NC-ND 4.0
Topological Closure Drives Structural Stabilization and Fast Cooperative Dynamics in Crowded Circular Polysomes
In linear polysomes, excluded-volume interactions among ribosomes can induce dimensional reduction of mRNA. Yet linear architectures allow steric stress to relax at open ends-- limiting how strongly crowding can remodel the mRNA's structure and dynamics. Using coarse-grained molecular-dynamics simul
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