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Calprotectin-Directed Humira® Maintenance Therapy (CADHUM)

Peter Higgins · 2013
ClinicalTrials.gov · Datasets · License: Public Domain · 2013
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biomarkerscrohn-s-diseaseibdinflammatory-bowel-disease
This is a study that invites adults with Crohn's disease and have been responding well to Adalimumab (Humira ®) for at least 6 months. Patients frequently discontinue maintenance medications in Crohn's disease, particularly when in remission. Patients want to know that they truly need to take a medication, yet they don't want to have flares. The purpose of this study is to see that if we monitor the patient, along with looking at changes in their stool samples, we can safely stop the maintenance medication Adalimumab for up to 48 weeks, or add as-needed dosing only, and keep them in remission.
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