The Efficacy of the Administration of Fibrinogen in Liver Transplantation

Objective: * To evaluate the efficacy of preoperative administration of fibrinogen in liver transplantation by maintaining a preoperative plasma level equal to 2.9 g / L compared with placebo, reflecting a reduction in the number of RBC units transfused during the procedure. * To determine the influence of fibrinogen administration on mortality and survival of liver graft evaluated one year after the procedure. * To determine the safety of fibrinogen administration recording thrombotic complications evaluated during hospitalization or at least 30 days postoperatively.