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A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours

Cancer Research UK · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
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bladder-cancercervical-cancerendometrial-cancergastric-cancermelanomanon-small-cell-lung-cancer-nsclcovarian-cancertriple-negative-breast-cancer
This clinical trial is evaluating a drug called HMBD-001 (an anti-HER3 monoclonal antibody) in participants with advanced HER3 positive solid tumours. The main aims are to find out the best dose of HMBD-001 that can be given to participants alone and in combination with other anti-cancer agents, more about the potential side effects of HMBD-001 and how they can be treated, and what happens to HMBD-001 inside the body and how it affects cancer cells.
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