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Study of NMS-03597812 in Adult Patients With Relapsed/Refractory Acute Myeloid Leukemia

Nerviano Medical Sciences · 2024
ClinicalTrials.gov · Datasets · License: Public Domain · 2024
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leukemia
The aim of PERKA-812-003 study is to investigate the safety, pharmacokinetics and preliminary anti-tumor activity of treatment with NMS-03597812 as single agent in Relapsed/Refractory Acute Myeloid Leukemia (R/R AML) patients who have exhausted standard treatment, including a subset of patients with TP53 mutations. It is anticipated that combination with venetoclax will be further evaluated following a future protocol amendment, once the Recommended Range Dose (RDR) as single agent has been defined.
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