Does Machine Learning Outperform Traditional Fibrosis Scores in Predicting Liver Cirrhosis Risk? A Longitudinal EHR-Based Study

Objective: Develop and evaluate machine learning (ML) models for predicting incident liver cirrhosis (LC) one and two years before diagnosis using routinely collected electronic health record (EHR) data and compare their performance with the FIB-4 and APRI clinical scores. Methods: We conducted a re