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Feedback-Calibrated Protein Optimization with Batch-Aligned Tail Arbitration

Lin, Zefeng et al.
arXiv (All) · Papers
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Protein optimization aims to discover high-fitness sequences under a limited experimental budget. Existing machine-learning methods use task-specific predictors, biological priors, or ranking-aware objectives to guide which variants are tested in the next experimental round. However, these methods c
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