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Evaluating E. coli genome‐scale metabolic model accuracy with high‐throughput mutant fitness data

Bernstein, David B et al.
eScholarship · Papers
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The Escherichia coli genome‐scale metabolic model (GEM) is an exemplar systems biology model for the simulation of cellular metabolism. Experimental validation of model predictions is essential to pinpoint uncertainty and ensure continued development of accurate models. Here, we quantified the accur
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