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Cancer‐cell‐secreted extracellular vesicles target p53 to impair mitochondrial function in muscle

Ruan, Xianhui et al.
eScholarship · Papers
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Skeletal muscle loss and weakness are associated with bad prognosis and poorer quality of life in cancer patients. Tumor‐derived factors have been implicated in muscle dysregulation by inducing cachexia and apoptosis. Here, we show that extracellular vesicles secreted by breast cancer cells impair m
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