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Enantioselective Alkylation of Fused Bicyclic Pyridines Enabled by Chiral Lithium Amides as Traceless Auxiliaries
Pyridines and nitrogen containing heterocycles comprise a large portion of pharmaceutical compounds and have many practical applications. Herein, we describe a straightforward, enantioselective method for direct alkylation of fused bicyclic pyridines, using chiral lithium amides as traceless auxilia
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