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Pharmacokinetics and Dose Optimization of Ethambutol in Children on First-Line Antituberculosis Therapy: An Individual Patient Data Meta-Analysis
BACKGROUND: Tuberculosis affects over one million children annually. Ethambutol (EMB) is a key component of first-line therapy, but comprehensive pediatric pharmacokinetic studies have been lacking. METHODS: EMB concentrations and individual-level patient data from 3 studies were analyzed using nonl
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