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The prevalence of protein misfolding as a mechanism for hereditary deafness

Rose A. Gogal et al.
PLOS · Papers · License: CC BY 4.0
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geneticsprotein-structure-prediction
Hearing loss is the most common sensory deficit impacting ~5% of the world’s population. The Deafness Variation Database (DVD) is a public resource of deafness variants, containing 381,924 missense variants across 224 genes, with 303,577 classified as a variant of uncertain significance (VUS). To a
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