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Alternative Stimulation Mode and Location for Auditory Hallucination Neuromodulation Treatment

The University of Texas Health Science Center, Houston · 2025
ClinicalTrials.gov · Datasets · License: Public Domain · 2025
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mrinaschizophreniatranscranial-magnetic-stimulation
The purpose of the study is to test the hypothesis that functionally navigated repetitive TMS stimulations to the prefrontal cortex (PFC) modulate aberrant cortical electrical activities at PFC circuitry. The TMS location of the PFC site will be individually localized by the symptom-related functional connectivity between PFC and symptom related areas (such as the auditory and language processing cortex). The investigators predict that such modulation will correct abnormal activities in patients with schizophrenia, reduce symptoms, especially auditory hallucination, and improve working memory/sustained attention performance.
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