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RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates

Murdoch Childrens Research Institute · 2014
ClinicalTrials.gov · Datasets · License: Public Domain · 2014
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bacteremiainfectionnasepsis
Babies aged 0 to 90 days with a suspected infection requiring treatment with vancomycin will be recruited. They will be randomised to receive vancomycin as an intermittent infusion (over 1 hour) or as a continuous infusion (over 24 hours). The hypothesis is that administering vancomycin as a continuous infusion will result in improved attainment of target concentrations in blood at steady state (when the drug is in equilibrium) compared to intermittent infusion.
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