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Dynamic Changes of Torquetenovirus (TTV) Load in Chinese Renal Transplant Recipients

Tongji Hospital · 2023
ClinicalTrials.gov · Datasets · License: Public Domain · 2023
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infectionrejectionvirus
The goal of this observational study is to learn about dynamic changes of Torquetenovirus (TTV) load in Chinese renal transplant recipients. The main questions it aims to answer are: * Is there correlation between TTV load and rejection? * Is there correlation between TTV load and infection? * Can changes in the TTV load of kidney transplant recipients predict rejection or infection? Participants will: * receive 13 follow-up visits within 1 year after kidney transplantation * provide 2 ml of whole blood for TTV load testing and other related testing at each follow-up * provide 10 ml of whole blood for dd-cfDNA testing at four follow-ups (1, 3, 6 and 12 months after transplantation) * provide 1 ml of serum for donor-specific antibody testing at three follow-ups (1, 6 and 12 months after transplantation)
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