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SBRT as a Vaccination for Metastatic Melanoma

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · 2019
ClinicalTrials.gov · Datasets · License: Public Domain · 2019
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nivolumab
Immunotherapy with PD-1 blockade is a first-line treatment for patients with advanced melanoma, but unfortunately most patients progress on this therapy. Recent evidence suggests that radiation can enhance the immune response in the presence of checkpoint blockade. The investigators aim to determine if radiation can elicit increased immune responses in patients who have stable or progressive disease on nivolumab.
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