Amplification of Merkel Cell Polyomavirus From Skin Swabs

Background: * Polyomavirus are DNA-based viruses that infect vertebrates, including humans. Most people are not harmed by polyomavirus infection, but people with compromised immune systems may be harmed by these viruses, and are at greater risk for developing certain types of rare cancers. * A recently discovered virus called Merkel cell polyomavirus (MCV) is a type of skin infection commonly found in humans. By using skin swabs to collect MCV, researchers hope to develop a laboratory culture model of MCV for future research. Objectives: \- To use skin swabs to collect samples of Merkel cell polyomavirus for future study. Eligibility: \- Individuals 18 years of age and older who are employed in the National Cancer Institute's Laboratory of Cellular Oncology. Design: * Participants will wipe a cotton swab across their forehead and eyebrows, and break off the end of the swab into a microcentrifuge tube. This procedure will be performed after work hours. * No other treatment or procedure will be given as part of this protocol.