Evaluation of Non-invasive Measurements of Atherosclerosis in Cardiovascular Risk Stratification

Multiple risk factors contribute to atherosclerosis, which ultimately results in clinical manifestation of cardiovascular disease. Atherosclerosis results in both functional and morphological changes in the vessel wall, which can be measured by ultrasonography. The current study has been designed to 1. To evaluate whether non-invasive measurements of atherosclerosis are independent predictors of cardiovascular disease and 2. to delineate new biochemical parameters and genetic variations, allowing earlier and more effective preventive therapy 3. The investigators intend to set guidelines for use of NIMA in an outpatient setting to facilitate early detection of increased cardiovascular risk and monitor life-style and pharmaceutical interventions. In both the general population and in Familial Combined Hyperlipidemia.