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Effect of Citalopram on Chest Pain in Patients With Functional Chest Pain

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · 2022
ClinicalTrials.gov · Datasets · License: Public Domain · 2022
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Non-cardiac chest pain (NCCP) in the absence of musculoskeletal abnormalities, major esophageal motor disorders, gastroesophageal reflux or eosinophilic esophagitis is called functional chest pain (FCP). Most likely multiple factors play a role, such as esophageal hypersensitivity and enhanced perception. Citalopram and other antidepressants are proven to be effective in the treatment of functional gastrointestinal disorders such as irritable bowel syndrome. With this trial the investigators want to assess the effect of citalopram on symptoms of chest pain in patients with functional chest pain.
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