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Computational Insights into Mechanostability and Dissociation Dynamics of the Dengue Virus Envelope Protein Ectodomain Dimer Across pH and Temperature Gradients

Ropón-Palacios, Georcki et al.
arXiv (All) · Papers
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biological-physicsbiomoleculeschemical-physics
Dengue virus (DENV) is an enveloped flavivirus of major public health importance. Its envelope (E) protein mediates viral entry through homodimer dissociation and subsequent membrane fusion, making it one of the principal targets for antiviral strategies. To investigate the molecular determinants of
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