Europe PMC
open access
CHCHD2 and CHCHD10 promoted autophagic clearance of protein aggregates via GABARAPs
Mutations in mitochondrial protein CHCHD2 and its paralog CHCHD10 were identified in patients with Parkinson disease (PD), amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) or Alzheimer disease (AD). CHCHD2 and CHCHD10 mutations caused neurodegeneration in model animals as seen in p
Conceptio Open Archive
Analyze & explore related research in Conceptio
Connect this record directly into your research workflow or AI agent. Explore citations across open repositories, query full text, and export structured proof bundles.
This document is indexed with metadata only: full text is not available in the archive for this record. Open the official source ↗
Related documents
- iPSC Neurodegenerative Disease Initiative isogenic CAG repeat iPSC line for Huntingtons disease#422357
- Ending Parkinson's Disease#466045
- α-Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron-microglia communication#347838
- An Exploratory Clinical Trial in Early Stage Huntington's Disease Patients With SEN0014196#896852
- Canonical autophagy remains inactive in induced pluripotent stem cells and neuronal progenitor cells following DNA damage induced by BPDE or etoposide#273330
Record · ID 1157774
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Retrieved via Conceptio: every document is proof-bundled with source, license, and retrieval metadata.
Bring this data into your agent: Connect via MCP or API · 20 free credits to start · no card required
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive
Read the Docs → · View CLI source on GitHub · Conceptio Open Knowledge Archive