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PKD2L1 channels segregated to the apical compartment are the dual-mode pH sensor in cerebrospinal fluid-contacting neurons

Vitar M et al.
Europe PMC · Papers
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mouseneurosciencephspinal-cord
Cerebrospinal fluid-contacting neurons (CSFcNs) are GABAergic cells that surround the central canal (cc) of the spinal cord. Their soma is located sub-ependymally and they have a dendritic-like process that ends as a bulb (the so-called 'apical process'; ApPr) inside the cc. It remains unclear how t
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