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The Mitochondrial ubiquitin ligase MARCHF5 cooperates with MCL1 to inhibit Apoptosis in KSHV-transformed primary effusion lymphoma cell lines

Prasanth Viswanathan et al.
PLOS · Papers · License: CC BY 4.0
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Kaposi’s sarcoma-associated herpesvirus (KSHV) causes several malignancies in people with HIV including Kaposi’s sarcoma and primary effusion lymphoma (PEL). We have previously shown that PEL cell lines require myeloid cell leukemia-1 (MCL1) to inhibit apoptosis. MCL1 is an oncogene that is amplifi
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