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Transcription factor activity divergence across muscle atrophy conditions: A comparative analysis of spaceflight, aging, and disuse using decoupleR
Skeletal muscle atrophy arises from heterogeneous insults including spaceflight, aging, and immobilization. Prior studies have catalogued differentially expressed genes (DEGs) in each context, but the transcription factors (TFs) coordinating these programs remain inconsistently characterized across
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