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Technological approaches to tamoxifen nanoformulation: emphasis on modified chitosan-based nanoparticles: a review
Tamoxifen remains a cornerstone in the treatment of estrogen receptor-positive breast cancer, yet its clinical performance is limited by poor aqueous solubility, high lipophilicity, and interindividual variability associated with CYP2D6-mediated formation of its more potent active metabolites. These
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