bioRxiv / medRxiv
open access
CC BY 4.0
Targeting Dengue Virus NS3 Helicase: Biochemical and Computational Evaluation of Catechins from Camellia sinensis as Potential Therapeutic Leads
Dengue virus serotype 2 is a human pathogenic flavivirus encoding non-structural protein 3 (DEN2-NS3), a superfamily-2 viral helicase. DEN2-NS3 contains an N-terminal protease domain and a C-terminal RNA helicase/nucleoside 5'-triphosphatase (NTPase) domain essential for replication. The enzyme util
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