bioRxiv / medRxiv
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CC BY 4.0
A multiscale analysis of liver lobule fibrosis and its impact on drug propagation and metabolism - a DLA approach
Employing DLA methods, this paper explores the self-assembly of collagen fibers and resulting fibrosis at three scales up to the scale of regular lobule models. This allows a mechanistic exploration of the effects of collagen on drug transport (flow and diffusion) and metabolism. In addition, this m
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