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Study Of Lapatinib In Patients With Relapsed Or Refractory Inflammatory Breast Cancer

GlaxoSmithKline · 2005
ClinicalTrials.gov · Datasets · License: Public Domain · 2005
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breastneoplasms
This study was designed to determine how effective and safe a new investigational drug, lapatinib, is in treating patients with treatment refractory or relapsed inflammatory breast cancer. Tumor tissue collected pre-treatment and at Day 28 will be examined for biologic activity by IHC (immunohistochemistry). Treatment will consist of daily oral therapy with lapatinib. A patient may continue treatment as long as they are receiving benefit. Blood samples for hematology and chemistry panels, MUGA/ECHO (multigated acquisition/echocardiogram) exams and physical exams will be performed throughout the study to monitor safety.
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