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Bioavailability and Bioequivalence of Two Risdiplam Tablets in Healthy Participants

Hoffmann-La Roche · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
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The study is a randomized, single oral dose, crossover study in up to three parts to investigate the relative bioavailability and bioequivalence of two different formulations of risdiplam 5 mg (dispersible tablets) versus the current risdiplam oral solution formulation in healthy male and female participants. The effect of food on these two dispersible tablets and the current oral solution will be studied, as well as the effect of omeprazole on the dispersible tablets.
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