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Pregnancy in Type I Interferon Receptor (IFNAR2) Knockout Sheep Challenges the Accepted Paradigm for Pregnancy Recognition in Ruminants
The effects of type I interferons, including interferon tau (IFNT), previously thought to be the signal for pregnancy recognition in ruminants, are mediated by the type I interferon receptor (IFNAR), a heterodimer comprised of IFNAR1 and IFNAR2. The genes encoding IFNAR were disrupted in fetal fibro
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