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SAMD9/9L Innate Immunity: Antiviral Mechanisms and Evolutionary Trade-Offs of Multidomain Proteins
Sterile alpha motif domain-containing 9 and 9-like (SAMD9/9L) are large multidomain proteins with antiviral innate immune and cellular homeostasis functions. Initially characterized as tumor suppressors, they are now also recognized as antiviral restriction factors against diverse viruses, including
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