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Circuit and Plasticity Defects in the Developing Somatosensory Cortex of Fmr1 Knock-Out Mice

Ingrid Bureau et al.
HAL (France) · Papers
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Silencing of the Fmr1 gene causes fragile X syndrome. Although defects in synaptic plasticity in the cerebral cortex have been linked to cognitive impairments in Fmr1 knock-out ( ko ) mice, the specific cortical circuits affected in the syndrome are unknown. Here, we investigated the development of
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