HAL (France)
open access
The GPCRVP score reliably predicts the impact of GLP1R human variants on receptor function
Abstract Aims/hypothesis The glucagon-like peptide-1 receptor (GLP1R) is a key regulator of glucose homeostasis and body weight, and a major therapeutic target for type 2 diabetes and obesity. Individual disease risk and response to treatments may vary widely depending on the presence of missense va
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