Antibacterial activity, molecular docking, and in silico safety profiling of novel 3,10-dihydro-2H-1,3-oxazepino[7,6-b]indole derivatives

In this study, nine derivatives of 3,10-dihydro-2H-1,3-oxazepino[7,6-b]indole (1–9), which combine two bioactive pharmacophoric cores, were synthesized and tested for antibacterial activity against five pathogenic bacterial strains. The resazurin-based microdilution plate method was