bioRxiv / medRxiv
open access
ITK deficiency protects against autoimmune pulmonary hemorrhage by promoting Amphiregulin producing regulatory T cells
Pulmonary hemorrhage (PH) is a life-threatening manifestation of systemic autoimmunity caused by immune-mediated disruption of the alveolar capillary barrier. Despite high mortality, the molecular checkpoints that shift destructive inflammation toward protective immune regulation remain poorly defin
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