bioRxiv / medRxiv
open access
CC BY 4.0
Integrative multi-omics QTL colocalization maps regulatory architecture in aging human brain
Multi-trait QTL (xQTL) colocalization has shown great promises in identifying causal variants with shared genetic etiology across multiple molecular modalities, contexts, and complex diseases. However, the lack of scalable and efficient methods to integrate large-scale multi-omics data limits deeper
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