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Intestinal Permeability in Obesity

Assistance Publique - Hôpitaux de Paris · 2014
ClinicalTrials.gov · Datasets · License: Public Domain · 2014
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bariatric-surgerybody-weightintestinal-permeabilitymetabolic-diseasesnaobesity
In rodents, obesity is associated with changes in tight junctions' structure in small intestine, which impacts intestinal permeability and results in metabolic complications. Few data exist in human. We hypothesized that intestinal permeability is altered in obese subjects in comparison to lean subjects, linked to metabolic and inflammatory status and that these alterations are modified after gastric bypass.
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