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Study of the Role of Oncostatin M in Head and Neck Squamous Cell Carcinoma

Poitiers University Hospital · 2024
ClinicalTrials.gov · Datasets · License: Public Domain · 2024
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cytokinehead-and-neck-cancerna
The ROMCOR study will be interested in the impact and the role of oncostatin M (OSM), a cytokine belonging to IL-6 superfamily, in the physiopathology of head and neck squamous cell carcinoma. The study team will study the impact of the presence of OSM and its main receptor OSM-R2 on several survival outcomes (overall survival, progression free survival) by multiple technics such as immunohistochemistry, transcriptomic in situ assays and spatial transcriptomic. Furthermore, the study team will try to show a link between serum level of several cytokines and in situ tumoral OSM.
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