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Postoperative Effects of Propofol Versus Sevoflurane Anesthesia

Damanhour Teaching Hospital · 2021
ClinicalTrials.gov · Datasets · License: Public Domain · 2021
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cognitive-functioninflammatory-responseoxidative-stress
Background: The choice of appropriate anesthetics is essential to protect brain function, decrease perioperative complications, and provide high-quality care, and better quality of life. Objectives: To compare the efficacy and safety of propofol versus sevoflurane in patients undergoing elective, non-cardiac operations under general anesthesia. Methods: This was a randomized (1:1), parallel, phase four clinical trial; carried out on 44 patients, who were candidates for elective, non-cardiac operations under general anesthesia at our hospital. Patients were randomly allocated into two equal groups in which anesthesia was maintained with propofol infusion in group P and sevoflurane inhalation in group S.
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